Yuan Zhu Selected Research

Neurofibromin 1 (Neurofibromin)

1/2018	2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis.
12/2015	Latent tri-lineage potential of adult hippocampal neural stem cells revealed by Nf1 inactivation.
7/2015	Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia.
8/2012	ERK inhibition rescues defects in fate specification of Nf1-deficient neural progenitors and brain abnormalities.
2/2008	Influence of hormones and hormone metabolites on the growth of Schwann cells derived from embryonic stem cells and on tumor cell lines expressing variable levels of neurofibromin.
2/2008	The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells.
7/2002	Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation.

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Yuan Zhu Research Topics

Disease

52	Neoplasms (Cancer) 01/2022 - 05/2004
16	Rectal Neoplasms (Rectal Cancer) 03/2022 - 03/2005
12	Lymphoma (Lymphomas) 01/2021 - 09/2015
10	Glioma (Gliomas) 01/2021 - 07/2002
8	Infections 01/2022 - 04/2007
7	Central Nervous System Cavernous Hemangioma 04/2022 - 03/2009
7	T-Cell Lymphoma (Lymphoma, T Cell) 01/2021 - 09/2015
6	Glioblastoma (Glioblastoma Multiforme) 04/2022 - 10/2013
6	Neurofibromatosis 1 (Neurofibromatosis Type I) 10/2021 - 02/2008
5	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 10/2020
5	Inflammation (Inflammations) 10/2020 - 10/2003
5	Astrocytoma (Pilocytic Astrocytoma) 10/2015 - 07/2002
4	Neoplasm Metastasis (Metastasis) 01/2022 - 03/2003
4	Atherosclerosis 01/2022 - 12/2019
4	Adenocarcinoma 10/2021 - 12/2008
4	Breast Neoplasms (Breast Cancer) 07/2021 - 09/2008
4	Hyperlipidemias (Hyperlipidemia) 01/2021 - 03/2016
4	Body Weight (Weight, Body) 01/2021 - 03/2016
3	Parkinson Disease (Parkinson's Disease) 05/2022 - 02/2007
3	Wounds and Injuries (Trauma) 01/2022 - 05/2009
3	Medulloblastoma 01/2022 - 10/2018
3	Stomach Neoplasms (Stomach Cancer) 10/2021 - 01/2012
3	Necrosis 01/2021 - 10/2013
3	Fibrosis (Cirrhosis) 01/2021 - 01/2020
3	Virus Diseases (Viral Diseases) 10/2020 - 12/2015
3	Ischemia 04/2020 - 05/2001
3	Neurofibromatoses (Neurofibromatosis) 01/2018 - 02/2008
3	Arthritis (Polyarthritis) 01/2017 - 10/2003
3	Brain Ischemia (Cerebral Ischemia) 12/2014 - 08/2005
3	Carcinoma (Carcinomatosis) 04/2007 - 03/2003
2	Cicatrix (Scar) 03/2022 - 01/2019
2	Hemorrhage 02/2022 - 01/2021
2	Cerebral Hemorrhage 01/2022 - 01/2021
2	Salmonella Infections (Salmonellosis) 01/2022 - 01/2021
2	Brain Edema (Cerebral Edema) 01/2022 - 10/2015
2	Ischemic Stroke 01/2022 - 04/2021
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 08/2021 - 03/2021
2	Flatfoot (Flat Feet) 08/2021 - 10/2017
2	Pathologic Constriction (Stenosis) 04/2021 - 04/2007
2	Sepsis (Septicemia) 01/2021 - 04/2020
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2021 - 05/2001
2	Critical Illness (Critically Ill) 01/2021 - 01/2021
2	COVID-19 01/2021 - 01/2020
2	Obesity 01/2021 - 01/2019
2	Extranodal NK-T-Cell Lymphoma 01/2021 - 10/2018
2	Type 2 Diabetes Mellitus (MODY) 01/2021 - 01/2019
2	Osteoarthritis 11/2020 - 11/2020
2	Hepatocellular Carcinoma (Hepatoma) 08/2020 - 06/2016
2	Acute Kidney Injury (Acute Renal Failure) 04/2020 - 10/2016

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 01/2021 - 05/2002
13	Biomarkers (Surrogate Marker)IBA 01/2022 - 09/2011
7	Neurofibromin 1 (Neurofibromin)IBA 01/2018 - 07/2002
6	CholesterolIBA 01/2021 - 03/2016
5	Biological ProductsIBA 01/2022 - 01/2013
5	Messenger RNA (mRNA)IBA 01/2021 - 05/2001
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2017 - 08/2005
4	Capecitabine (Xeloda)FDA Link 01/2022 - 03/2015
4	AnthracyclinesIBA 01/2021 - 12/2018
4	Pharmaceutical PreparationsIBA 10/2020 - 06/2010
4	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2018 - 02/2007
3	RNA (Ribonucleic Acid)IBA 06/2022 - 03/2017
3	Indicators and Reagents (Reagents)IBA 05/2022 - 10/2016
3	Temozolomide (Temodar)FDA LinkGeneric 04/2022 - 02/2016
3	IronIBA 01/2022 - 09/2010
3	Oxaliplatin (Eloxatin)FDA LinkGeneric 11/2021 - 03/2015
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 10/2021 - 11/2016
3	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2021 - 12/2015
3	Viral RNAIBA 01/2021 - 12/2015
3	Therapeutic UsesIBA 11/2020 - 06/2008
3	ProdrugsIBA 10/2020 - 12/2016
3	MicroRNAs (MicroRNA)IBA 01/2020 - 10/2016
3	Mitogen-Activated Protein KinasesIBA 01/2018 - 01/2017
3	AntioxidantsIBA 11/2016 - 04/2012
3	Oxygen (Dioxygen)IBA 12/2014 - 02/2007
2	Long Noncoding RNAIBA 06/2022 - 01/2019
2	Anticonvulsants (Antiepileptic Drugs)IBA 12/2021 - 01/2017
2	LipidsIBA 01/2021 - 07/2020
2	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2021 - 01/2020
2	Amyloid (Amyloid Fibrils)IBA 01/2021 - 10/2020
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2021 - 09/2015
2	Triglycerides (Triacylglycerol)IBA 01/2021 - 03/2016
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 02/2007
2	DNA (Deoxyribonucleic Acid)IBA 12/2020 - 08/2005
2	LubricantsIBA 11/2020 - 11/2020
2	oxidized low density lipoproteinIBA 10/2020 - 03/2016
2	Apolipoproteins E (ApoE)IBA 10/2020 - 07/2020
2	Peptides (Polypeptides)IBA 10/2020 - 10/2020
2	GTPase-Activating Proteins (GTPase-Activating Protein)IBA 10/2020 - 06/2004
2	Cisplatin (Platino)FDA LinkGeneric 04/2020 - 10/2016

Therapy/Procedure

29	Therapeutics 04/2022 - 05/2004
22	Radiotherapy 01/2022 - 03/2003
15	Drug Therapy (Chemotherapy) 01/2022 - 03/2005
10	Chemoradiotherapy 01/2022 - 03/2005
7	Neoadjuvant Therapy 03/2022 - 03/2005
3	Osteotomy 12/2018 - 06/2016
3	Oral Administration 11/2016 - 12/2005
3	Transplantation 02/2016 - 08/2005
2	Debridement 08/2021 - 05/2009
2	Contraindications 01/2021 - 03/2003
2	Microspheres (Microsphere) 11/2020 - 11/2020